Published in the American Journal of Epidemiology, the prospective study of couples trying to conceive found no association between COVID-19 vaccination and fecundability — the probability of conception per menstrual cycle — in female or male partners who received the Pfizer-BioNTech, Moderna, or Johnson & Johnson vaccines.
In contrast, the findings indicate that COVID-19 infection among males may temporarily reduce fertility, an outcome that could be avoidable through vaccination.
“Many reproductive-aged individuals have cited concerns about fertility as a reason for remaining unvaccinated,” says study lead author Dr. Amelia Wesselink, research assistant professor of epidemiology at BUSPH.
“These data provide reassuring evidence that COVID vaccination in either partner does not affect fertility among couples trying to conceive,” says study senior author Dr. Lauren Wise, professor of epidemiology at BUSPH. The new data also help quell concerns about COVID-19 vaccines and fertility that arose from anecdotal reports of females experiencing menstrual cycle changes following vaccination.